Stratification for Confounding – Part 1: The Mantel-Haenszel Formula
نویسندگان
چکیده
منابع مشابه
Stratification for confounding--part 1: the Mantel-Haenszel formula.
Stratification allows to control for confounding by creating two or more categories or subgroups in which the confounding variable either does not vary or does not vary very much. The Mantel-Haenszel formula is applied in cohort and in case-control studies to calculate an overall, unconfounded, effect estimate of a given exposure for a specific outcome by combining stratum-specific relative ris...
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In many epidemiological studies, disease occurrences and their rates are naturally modelled by counting processes and their intensities, allowing an analysis based on martingale methods. Applied to the Mantel–Haenszel estimator, these methods lend themselves to the analysis of general control selection sampling designs and the accommodation of time-varying exposures.
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This paper proposes two new Mantel-Haenszel test statistics for correlated binary data in 2 x 2 tables that are asymptotically valid in both sparse data (many strata) and large-strata limiting models. Monte Carlo experiments show that the statistics compare favorably to previously proposed test statistics, especially for 5-25 small to moderate-sized strata. Confidence intervals are also obtaine...
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Several statistical methods have been developed for adjusting the Odds Ratio of the relation between two dichotomous variables X and Y for some confounders Z. With the exception of the Mantel-Haenszel method, commonly used methods, notably binary logistic regression, are not symmetrical in X and Y. The classical Mantel-Haenszel method however only works for confounders with a limited number of ...
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S Three new test statistics are introduced for correlated categorical data in strati ed R C tables. They are similar in form to the standard generalized Cochran-Mantel-Haenszel statistics but modi ed to handle correlated outcomes. Two of these statistics are asymptotically valid in both many-strata (sparse data) and large-strata limiting models. The third one is designed speci cally for the man...
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ژورنال
عنوان ژورنال: Nephron Clinical Practice
سال: 2010
ISSN: 1660-2110
DOI: 10.1159/000319590